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ACSQHC-ARCR-447

Prioritised clinical domain
Adult critical care
Abbreviation
EXCEL
Registry contact

Carol Hodgson, Monash University, carol.hodgson@monash.edu

Year established
2019
Description

The use of ECMO is associated with significant costs and risks, and it requires specialist training and expertise. In order to better prepare for the organisation of these complex interventions in the ICU across regions, we need to have accurate data on patients undergoing ECMO. 

The EXCEL registry represents a novel, coordinated effort to create a high-quality, detailed, prospective registry of patients requiring ECMO at Australian ECMO centres. EXCEL includes data on ECMO retrieval, imitation, patient selection, device, cannula and person cannulating, daily data for 7 days, complications, costs and PROMs (HRQoL, disability, return to work, cognitive function) at 6 and 12 months. Additionally we have 4 embedded clinical trials. 

EXCEL can be used to address specific safety concerns, clinical questions and process of care issues. As a result, EXCEL can be designed and implemented to answer new investigator-initiated, hypothesis-driven clinical questions. We currently have 4 embedded clinical trials.

Reporting process
  • Feedback to contributing clinicians - Quarterly reports provided to each participating hospital.
  • Shared with clinicians
  • Reported in Annual Report
  • Shared with consumers
  • Shared with hospital executive
  • Shared with medical colleges
  • Heart Foundation Website
  • Reported to State/Territory health departments - To commence in June 2020
Patient Reported Outcome Measures (PROMs)

EQ5D-5L, WHODAS 2.0, ADL, IADL, Modified Rankin Scale and MoCA Blind

Patient Reported Experience Measures (PREMs)

Nil

Participating sites

Australian Capital Territory

  • Canberra Hospital

New South Wales

  • John Hunter Hospital
  • Liverpool Hospital
  • Prince of Wales Hospital
  • Royal North Shore Hospital
  • Royal Prince Alfred Hospital
  • St George Hospital
  • St Vincent’s Hospital Sydney
  • Westmead Hospital

Queensland

  • Gold Coast University Hospital
  • Prince Charles Hospital
  • Princess Alexandra Hospital
  • Royal Brisbane and Women’s Hospital
  • Townsville Hospital

South Australia

  • Flinders Medical Centre
  • Royal Adelaide Hospital

Tasmania

  • Launceston Hospital
  • Royal Hobart Hospital

Victoria

  • Alfred Hospital
  • Austin Hospital
  • Box Hill Hospital
  • Epworth Hospital
  • Frankston Hospital
  • Monash Medical Centre
  • Royal Melbourne Hospital
  • St Vincent’s Melbourne
  • University Hospital Geelong

Western Australia

  • Fiona Stanley Hospital
  • Sir Charles Gairdner Hospital

New Zealand

  • Auckland Hospital
Condition
Patients with cardiac arrest, acute cardiac failure or acute respiratory failure requiring extracorporeal membrane oxygenation
Name
Australian and New Zealand extracorporeal membrane oxygenation (ECMO) registry
Lead organisation
Monash University
Ethics approval reference
43134/Alfred Health HREC
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