Australian Passive Antimicrobial Resistance Surveillance (APAS) – third-generation cephalosporin resistance in Escherichia coli and Klebsiella pneumoniae: prevalence of extended-spectrum β-lactamase (ESBL) phenotype
This report provides analyses of trends for resistance to third-generation cephalosporins, such as ceftriaxone, in E. coli and K. pneumoniae captured through APAS from 2006 to 2021.
Resistance to third-generation cephalosporins is a feature of organisms that produce extended-spectrum β-lactamases (ESBLs). This type of resistance has important implications for infection prevention and control and antimicrobial stewardship programs.
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